OU is a 20-point favorite over the Cyclones

Oct 29, 2016; Norman, OK, USA; Oklahoma Sooners quarterback Baker Mayfield (6) is pursued by Kansas Jayhawks safety Fish Smithson (9) during the second quarter at Gaylord Family – Oklahoma Memorial Stadium. Mandatory Credit: Mark D. Smith-USA TODAY Sports

In the century-plus history of Iowa State football, the Cyclones have only beaten Oklahoma five times.

Las Vegas is not predicting No. 6 to come in Thursday night’s 6:30 kick on ESPN. In fact, the experts in the desert have tabbed the Sooners as a 20-point favorite.

Iowa State (1-7, 0-5) lost to Kansas State 31-26 on Saturday.

The Sooners (6-2, 5-0) throttled Kansas 56-3.

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